32245-65-1 Usage
Uses
Used in Pharmaceutical and Bioconjugate Production:
(D,L)-Cbz-ε-hydroxynorleucine is used as a building block for the synthesis of pharmaceuticals and bioconjugates, due to its ability to be incorporated into peptide chains and interact with enzymes and receptors. This makes it a valuable component in the development of therapeutic agents.
Used in Drug Delivery Systems:
(D,L)-Cbz-ε-hydroxynorleucine is used as a component in the design and development of drug delivery systems. Its interaction with enzymes and receptors can be leveraged to improve the targeting and efficacy of drug delivery, potentially enhancing the treatment of various diseases.
Used in Research of Protein Structure and Function:
(D,L)-Cbz-ε-hydroxynorleucine is used as a research tool for studying protein structure and function. Its unique properties allow it to be used in the investigation of enzyme mechanisms, receptor interactions, and other aspects of protein biology.
Used in the Development of Novel Biomaterials:
(D,L)-Cbz-ε-hydroxynorleucine is used as a starting material in the development of new biomaterials. Its potential applications in this field include the creation of biocompatible materials for use in medical devices, tissue engineering, and other biotechnological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 32245-65-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,4 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 32245-65:
(7*3)+(6*2)+(5*2)+(4*4)+(3*5)+(2*6)+(1*5)=91
91 % 10 = 1
So 32245-65-1 is a valid CAS Registry Number.
32245-65-1Relevant academic research and scientific papers
Synthesis of 2-Desoxy-α-O-glycopeptides by the N-Iodosuccinimide (NIS) Procedure
Kottenhahn, Matthias,Kessler, Horst
, p. 727 - 744 (2007/10/02)
Glycosidation of amino acid/peptide derivatives of serine, threonine, or hydroxyproline with glycals like tris-O-acetyl-D-glucal 1 or tris-O-acetyl-D-galactal 2 and N-iodosuccinimide (NIS) gives 2-deoxy-2-iodo-α-O-glycopeptides with high yields and excell
Microbial Iron Chelators: Total Synthesis of Aerobactin and Its Constiruent Amino Acid, N6-Acetyl-N6-hydroxylysine
Maurer, Peter J.,Miller, Marvin J.
, p. 3096 - 3101 (2007/10/02)
The synthesis of the natural ferric ionophore (-)-aerobactin (1) and of its constituent amino acid N6-acetyl-N6-hydroxylysine (2) is described.The benzyl hydroxamates * and ( were subjected to triphenylphosphine-diethyl azodicarboxylate-mediated alkylations with the ε-hydroxynorleucine derivative 7a.While * gave a complex mixture with predominant carbonyl O-alkylation, 9 was cleanly N-alkylated to yield 14.Compounds 10a,b were prepared by direct alkylation of 8 with bromides 15a,b which gave predominant N-alkylation.Hydrogenation of (D,L)-10a yielded (D,L)-N-6- acetyl-N6-hydroxylysine (2).Optically active 10b, prepared from (L)-ε-hydroxynorleucine, was α-N deprotected and coupled with anhydromethylenecitryl chloride (18) to yield 19, which was deprotected in two steps to yield (-)-aerobactin (1).
