322473-94-9Relevant academic research and scientific papers
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety
Ho, Ginny D.,Anthes, John,Bercovici, Ana,Caldwell, John P.,Cheng, Kuo-Chi,Cui, Xiaoming,Fawzi, Ahmad,Fernandez, Xiomara,Greenlee, William J.,Hey, John,Korfmacher, Walter,Lu, Sherry X.,McLeod, Robbie L.,Ng, Fay,Torhan, April Smith,Tan, Zheng,Tulshian, Deen,Varty, Geoffrey B.,Xu, Xiaoying,Zhang, Hongtao
scheme or table, p. 2519 - 2523 (2009/12/25)
The discovery of 1 as a high-affinity ligand for the nociceptin receptor has led to the synthesis of a series of tropane (8-methyl-8-azabicyclo[3.2.1]octane) derivatives as optimized ligands. These compounds exhibit high affinity for the nociceptin recept
