32281-91-7 Usage
Chemical Class
Sulfamide derivative
Molecular Weight
407.26 g/mol
Physical Appearance
White crystalline solid
Solubility
Soluble in DMSO, poorly soluble in water
Mechanism of Action
Selective inhibitor of receptor-operated calcium channels (ROCCs); potent and selective blocker of TRPC channels
Therapeutic Applications
Potential treatment for hypertension, cardiac arrhythmias, and neurodegenerative diseases
Cellular Processes Modulation
Proliferation, migration, and apoptosis
Research Utility
Valuable tool for studying the role of calcium signaling in physiological and pathological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 32281-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,8 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32281-91:
(7*3)+(6*2)+(5*2)+(4*8)+(3*1)+(2*9)+(1*1)=97
97 % 10 = 7
So 32281-91-7 is a valid CAS Registry Number.
32281-91-7Relevant academic research and scientific papers
The Reaction of Malononitrile with Some Enamines of 1-Indanone. Synthesis of o-Aminonitriles of Indenopyridine and Indenothiopyran
Bogdanowicz-Szwed, Krystyna,Feret, Hanna,Lipowska, Malgorzata
, p. 623 - 627 (2007/10/02)
The reaction of enamines of 1-oxo-indan-2-carboxylic acid anilides (1) with malononitrile yielded 2-arylcarbamylindenylidene-malononitriles (3), which in alkaline solution underwent cyclization to indenopyridines (4).Enamines of 1-oxo-indan-2-carbothionic acid anilides (2) reacted with malononitrile yielding indenothiopyrans (6), which under influence of alkalis were transformed to indenopyridines (8). - Enamines of β-Ketoacid Anilides, o-Aminonitriles, Indenopyridine, Indenothiopyran
