3229-53-6

Usage

InChI:InChI=1/C8H16NO/c1-7(2)5-6-8(3,4)9(7)10/h5-6H2,1-4H3

Upstream product

• 4567-22-0 2,2,5,5-tetramethylpyrrolidine 
• 4567-19-5 2,2,5,5-tetramethylpyrrolidinyl-1-oxy 
• 4567-18-4 2,5,5-trimethylpyrroline N-oxide 
• 4604-49-3 5-methyl-5-nitrohexan-2-one 
• 5167-85-1 2,2,5,5-tetramethyl-3-oxopyrrolidine 
• 826-36-8 2,2,6,6-Tetramethyl-4-piperidone 
• 917-64-6 methyl magnesium iodide 
• 57167-75-6 3,5-dibromo-2,2,6,6-tetramethylpiperidin-4-one 
• 19805-75-5 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide 

Downstream Products

• 73743-16-5 O-benzoyl-NN-(1,1,4,4-tetramethyltetramethylene)hydroxylamine 
• 250337-70-3 1,2- diphenyl–2-((2,2,6,6-tetramethylpiperidin-1-yl)oxy)ethan-1-one 

Relevant academic research and scientific papers

INFLUENCE OF CHEMICAL STRUCTURE OF NITROXYL SPIN LABELS ON THEIR REDUCTION BY ASCORBIC ACID

The influence of structure on the reduction of nitroxyl spin labels by ascorbic acid was examined using both piperidine and pyrrolidine nitroxyls.A five-fold molar excess of ascorbic acid and pH of 7.4 were used.The nitroxyl concentration was measured by electron spin resonance spectrometry.The five-membered (pyrrolidine) nitroxyls were more stable than the six-membered derivatives.Ring substituents also influenced the reaction.The anionic derivatives were more stable than the unionized compounds which, in turn, were more stable than the amines (cations at pH 7.4).

Homosolvolysis

Nitroxides, when used as solvents, promote the homolysis of a variety of weak bonds.Strong chemical evidence for the formation of free radicals is confirmed by e.s.r. studies in which the formation of free radicals has been monitored.This fission of single bonds of solute molecules dissolved in solvents with unpaired electrons is called homosolvolysis, in contrast to the common bond fission observed in polar solvents which is called heterosolvolysis.