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Tosifen, a triazolopyridine derivative, is a potent and selective inhibitor of protein kinase C theta (PKCθ), which is essential in the regulation of T-cell activation and function. Its ability to inhibit PKCθ has demonstrated potential in treating autoimmune diseases and certain types of cancer, making tosifen a valuable therapeutic agent for immune-mediated and inflammatory conditions.

32295-18-4

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32295-18-4 Usage

Uses

Used in Pharmaceutical Industry:
Tosifen is used as an immunosuppressive agent for its role in inhibiting PKCθ, which is crucial in T-cell activation and function. This makes it a potential treatment for autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.
Used in Oncology:
Tosifen is used as an anti-cancer agent due to its potential to inhibit the proliferation and survival of cancer cells by targeting PKCθ, a protein involved in these processes. Its investigation for anti-cancer properties highlights its potential in treating certain types of cancer.
Used in Drug Development:
Tosifen is utilized in the development of therapeutic agents for immune-mediated and inflammatory diseases, as well as in the research and development of treatments for specific cancers, given its demonstrated effects on PKCθ inhibition.

Check Digit Verification of cas no

The CAS Registry Mumber 32295-18-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,9 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 32295-18:
(7*3)+(6*2)+(5*2)+(4*9)+(3*5)+(2*1)+(1*8)=104
104 % 10 = 4
So 32295-18-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H20N2O3S/c1-13-8-10-16(11-9-13)23(21,22)19-17(20)18-14(2)12-15-6-4-3-5-7-15/h3-11,14H,12H2,1-2H3,(H2,18,19,20)

32295-18-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-methylphenyl)sulfonyl-3-[(2S)-1-phenylpropan-2-yl]urea

1.2 Other means of identification

Product number -
Other names Tosifeno

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32295-18-4 SDS

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