32305-30-9Relevant academic research and scientific papers
A rapid, chromatography-free route to substituted acridine-isoalloxazine conjugates under microwave irradiation
Johns, Stephen C.,Crouch, Laurie L.E.,Grieve, Stephen,Maloney, Holly L.,Peczkowski, Gary R.,Jones, Allison E.,Sharp, Duncan,Smith, Robert B.
supporting information, p. 3308 - 3311 (2014/06/09)
Microwave irradiation was applied to a sequence of condensation reactions from readily available 9-chloroacridines to provide a range of novel acridine-isoalloxazine conjugates. The combination of these two moieties, both of biological interest, was achieved by a chromatography-free route.
Fast synthesis of substituted N-phenylanthranilic acids using Ullmann condensation under microwave irradiation in dry media
Martin, Ana,Mesa, Miriam,Docampo, Maite L.,Gomez, Victoria,Pellon, Rolando F.
, p. 271 - 277 (2007/10/03)
Substituted N-phenylanthranilic acids using the Ullmann condensation under microwave irradiation in dry media were obtained in good yield and short reaction times. Copyright Taylor & Francis LLC.
Microwave-assisted synthesis of N-phenylanthranilic acids in water
Martin, Ana,Pellon, Rolando F.,Mesa, Miriam,Docampo, Maite L.,Gomez, Victoria
, p. 561 - 563 (2007/10/03)
N-Phenylanthranilic acid derivatives were synthesised using the Ullmann condensation of 2-chlorobenzoic acid with aniline derivatives under microwave irradiation in aqueous media. The method offers better yields in shorter reaction times compared to classical heating approaches using water as solvent.
Influence of the reaction conditions in the N-alkylation of acridone-2-Carboxylic acids
Marill,Pellon Comdom,Hernandez
, p. 2159 - 2167 (2007/10/03)
The synthesis and a study about the influence of the solvent in the alkylation reaction of 2-Carboxy-6-chloro-9(10H) acridone (3b) and 2-Carboxy-6-chloro-7-nitro-9(10H) acridone (3a) was done, obtaining the N-ethyl ester derivative of the alkylated produc
The Intercalation of 6-Chloro-substituted-9-amino>acridines with DNA
Kitchen, S. E.,Wang, Yueh-Hwa,Baumstark, A. L.,Wilson, W. D.,Boykin, D. W.
, p. 940 - 944 (2007/10/02)
A series of 6-chloro-2-substituted -9-amino>acridines has been prepared.The binding affinities and the unwinding angles for the acridine derivatives, relative to ethidium, were determined from viscometric titrations with ccs-DNA.
