323196-47-0Relevant academic research and scientific papers
Total synthesis of mololipids: A new series of anti-HIV moloka'iamine derivatives
Schoenfeld, Ryan C.,Lumb, Jean-Philip,Fantini, Jacques,Ganem, Bruce
, p. 2679 - 2681 (2000)
A new family of bioactive bromotyrosine derivatives, termed mololipids, was recently isolated from a Hawaiian sponge, but could not be resolved into individual components by chromatography. To complete their structural characterization and better understand structure-activity relationships, the first pure samples of dimyristoyl, distearoyl, dioleoyl, and stearoyl/oleoyl mololipids have now been prepared by total synthesis, and their anti-HIV activity investigated. (C) 2000 Published by Elsevier Science Ltd.
