Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer) is a chemical compound formed from the dimerization of Adefovir Dipivoxil (A280465), which is an oral reverse transcriptase inhibitor used in the treatment of hepatitis B. The presence of this dimer indicates the degradation of Adefovir Dipivoxil under specific conditions, suggesting that the stability of Adefovir Dipivoxil is compromised under such circumstances.
323201-05-4
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Basic information
- Product Name: Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer )
- Synonyms: Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer ) ;Adefovir Dipivoxil Dimer;Adefovir Dipivoxil Impurity B;((((2-(6-((((9-(2-(phosphorylmethoxy)ethyl)-9H-purin-6-yl)amino)methyl)amino)-9H-purin-9-yl)ethoxy)methyl)phosphoryl)tetrakis(oxy))tetrakis(methylene) tetrakis(2,2-dimethylpropanoate);Adefovir Impurity F
- CAS NO:323201-05-4
- Molecular Formula: C41H64N10O16P2
- Molecular Weight: 1014.95
- EINECS: N/A
- Product Categories: N/A
- Mol File: 323201-05-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 1009.4±75.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.38±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
- Solubility: DMSO (Slightly), Methanol (Slightly)
- PKA: 3.17±0.10(Predicted)
- CAS DataBase Reference: Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer )(CAS DataBase Reference)
- NIST Chemistry Reference: Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer )(323201-05-4)
- EPA Substance Registry System: Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer )(323201-05-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 323201-05-4(Hazardous Substances Data)
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323201-05-4 Usage
Uses
Used in Pharmaceutical Industry:Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer) is used as a degradation product in the development and manufacturing process of Adefovir Dipivoxil. Its presence helps in understanding the stability and degradation pathways of Adefovir Dipivoxil, which is crucial for ensuring the quality, safety, and efficacy of the drug.
Additionally, the study of Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer) can aid in the optimization of manufacturing processes, formulation development, and storage conditions to minimize its formation and improve the overall stability of Adefovir Dipivoxil. This, in turn, contributes to the effective treatment of hepatitis B patients and the overall success of the pharmaceutical product.
Check Digit Verification of cas no
The CAS Registry Mumber 323201-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,3,2,0 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.Calculate Digit Verification of CAS Registry Number 323201-05:
(8*3)+(7*2)+(6*3)+(5*2)+(4*0)+(3*1)+(2*0)+(1*5)=74
74 % 10 = 4
So 323201-05-4 is a valid CAS Registry Number.
323201-05-4Upstream product
323201-05-4Downstream Products
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Adefovir dipivoxyl impuritiesb (adefovir dipivoxyl dimer )
