32337-84-1Relevant academic research and scientific papers
Experimental and Theoretical Investigations of the Bromination of Phenols with β and γ Aliphatic Substituents, including Rings
Zhang, Jinsong,Chang, Xiao,Bowman, Erich C.,Holt, Carter J.,Lodewyk, Michael W.,Miller, Randy M.,Xia, Guangming
, p. 9292 - 9296 (2015)
Bromination reactions of substituted and ring fused phenols were studied by both experiment (t-BuNH-Br) and computation (density functional theory). The outcomes support each other, indicating a clear and predictable regioselective preference among 3,4-bis-alkylated and 3,4-ring-fused phenols.
Double-ring-substituted pyrazolone azo compound, its preparation and use
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Paragraph 0122-0125, (2018/09/02)
The invention belongs to the fields of the pharmaceuticals and the chemical engineering, and relates to bicyclic-substituted pyrazolone azo compounds, and a preparation method and a use thereof, and concretely relates to compounds represented by formula I, or pharmaceutically acceptable salts or solvates thereof, wherein L and R1 to R6 are defined as in the specification and the claims. The invention also relates to a preparation method of the compounds of formula I, a medicinal composition of the compounds, and a medicinal use of the compounds. The compounds of formula are an effective TOP receptor stimulant, and are a good thrombocytopenia treatment drug.
SUBSTITUTED PYRAZINE DERIVATIVES
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Page/Page column 57, (2010/02/07)
The present invention provides substituted pyrazine derivatives of Formula (I), that are CRF1 receptor antagonists, including human CRF1 receptors. This invention also relates to use of compounds of the invention for treating a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders, particularly anxiety-related disorders and mood disorders.
