32353-97-2

Basic information

• Product Name: (E)-4,4'-(prop-1-ene-1,3-diyldisulfonyl)bis(chlorobenzene)
• Synonyms: (E)-4,4'-(prop-1-ene-1,3-diyldisulfonyl)bis(chlorobenzene)
• CAS NO: 32353-97-2
• Molecular Weight: 391.296
• Mol File: 32353-97-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-4,4'-(prop-1-ene-1,3-diyldisulfonyl)bis(chlorobenzene)(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4,4'-(prop-1-ene-1,3-diyldisulfonyl)bis(chlorobenzene)(32353-97-2)
• EPA Substance Registry System: (E)-4,4'-(prop-1-ene-1,3-diyldisulfonyl)bis(chlorobenzene)(32353-97-2)

Safety Data

• Hazardous Substances Data: 32353-97-2(Hazardous Substances Data)

Upstream product

• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 20058-13-3 p-Chlor-phenyl-(2,3-dibrom-propyl)-sulfon 
• 3729-44-0 1-(allylsulfonyl)-4-chlorobenzene 

Relevant articles and documents

A practical synthesis of functionalized isoindolinones via [3?+?3] benzannulation of 1,3-bissulfonylpropenes and 4-arylmethylene-2,3-dioxopyrrolidines

A straightforward synthesis of isoindolinones has been developed via a [3 + 3] benzannulation of 4-arylmethylene-2,3-dioxopyrrolidines and 1,3-bissulfonylpropenes (or 4-sulfonylcrotonates). A series of functionalized isoindolinones were obtained in excellent yields. The reaction could be carried out under mild conditions without transition metal catalyst. The finding provides a practical approach for the preparation of isoindolinone derivatives with potential biological activities.

Direct N-H/α,α,β,β-C(sp3)-H functionalization of piperidine via an azomethine ylide route: synthesis of spirooxindoles bearing 3-substituted oxindoles

A protocol for the direct functionalization of N-H/α,α,β,β-C(sp3)-H of piperidine without any metal or external oxidants is reported. This reaction is promoted by 4-(trifluoromethyl)benzoic acid via an azomethine ylide intermediate. This is a simple method for the synthesis of spirooxindoles bearing 3-substituted oxindole moieties.