323579-72-2

Upstream product

• 104637-87-8 (E)-enol lactone of α-(2-furfurylidene)-β-(p-methoxybenzoyl)propionic acid 

Downstream Products

• 323579-82-4 3-Chloro-propionic acid N'-[2-[1-furan-2-yl-meth-(E)-ylidene]-4-(4-methoxy-phenyl)-4-oxo-butyryl]-hydrazide 
• 432542-72-8 N-(N'-{3-furan-2-yl-2-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-acryloyl}-hydrazinocarbonyl)-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

A facile method for the synthesis of 6-aryl-1-(3-chloropropanoyl)-4-[(E)-1- (2-furyl)methylidene)]-1,2,3,4-tetrahydr o-3-pyridazinones and 2-(2-chloroethyl)-5-[α-aracyl-β-(2-furyl)]-(E )-vinyl-1,3, 4-oxadiazoles

The 6-aryl-1-(3-chloropropanoyl)-4-[(E)-1-(2-furyl)methylidene)]-1,2,3,4- tetra-hydro-3-pyridazinones (6a-d) were synthesized by the reaction of acid chloride 3 with α-aracyl(β-2-furyl)acrylic acid hydrazides (2a-d) in a high yield, one pot reaction. On the other hand, 2-(2-chloroethyl)-5-[α- aracyl-β-(2-furyl)]-(E)-vinyl-1,3,4-oxadiazoles (7a-d) were also prepared by cyclodehydration of N1[α-aracyl-β-(2-furyl)acroyl- N2[3-chloro-propanoyl] hydrazine derivatives (4a-d). The proposed structures of the products were confirmed by elemental analysis, spectral data and chemical evidence.