323582-27-0

Upstream product

• 323582-25-8 1-(tert-butyl-dimethyl-silanyloxy)-4,4-bis-phenylsulfanyl-butan-2-ol 
• 31167-05-2 2,4-bis-trimethylsilyloxy-5-ethylpyrimidine 
• 4212-49-1 5-ethyluracil 
• 3561-67-9 bis(phenylthio)methane 
• 78906-15-7 tert-butyldimethylsilyl (S)-glycidyl ether 

Downstream Products

• 323582-29-2 2-(tert-butyl-dimethyl-silanyloxymethyl)-7-ethyl-4-phenylsulfanyl-3,4-dihydro-2H-pyrimido[2,1-b][1,3]oxazin-8-one 

Relevant academic research and scientific papers

A novel synthesis of 4'-thionucleosides and a potential stereospecific route to pyrimidine nucleosides

Starting with the L-ascorbate derived epoxide 1, a di-t-butyl dithioacetal cyclisation route to 2'-deoxy-4'-thionucleosides has been developed. Based on an intermediate in this route, a novel and stereospecific route to α- or β-pyrimidine nucleosides has been conceived, but its implementation failed at a key ring-closure step. (C) 2000 Elsevier Science Ltd.