α-Apopodophyllamine, also known as α-podophyllotoxin, is a naturally occurring lignan compound found in the roots and rhizomes of the Podophyllum peltatum plant, commonly known as mayapple. This chemical has been widely studied for its anti-cancer properties, as it inhibits the activity of topoisomerase II, an enzyme essential for DNA replication and transcription. Due to its ability to disrupt the cell cycle and induce apoptosis in cancer cells, α-apopodophyllamine has been used as a precursor in the synthesis of several chemotherapeutic agents, such as etoposide and teniposide, which are used to treat various types of cancer. However, it is important to note that α-apopodophyllamine itself is not used as a direct treatment due to its toxicity and side effects.
32384-14-8
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Basic information
- Product Name: α-apopodophyllamine
- Synonyms:
- CAS NO:32384-14-8
- Molecular Formula:
- Molecular Weight: 385.417
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: α-apopodophyllamine(CAS DataBase Reference)
- NIST Chemistry Reference: α-apopodophyllamine(32384-14-8)
- EPA Substance Registry System: α-apopodophyllamine(32384-14-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 32384-14-8(Hazardous Substances Data)
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32384-14-8 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 32384-14-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,3,8 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.Calculate Digit Verification of CAS Registry Number 32384-14:
(7*3)+(6*2)+(5*3)+(4*8)+(3*4)+(2*1)+(1*4)=98
98 % 10 = 8
So 32384-14-8 is a valid CAS Registry Number.
32384-14-8Upstream product
32384-14-8Downstream Products
- 78178-35-5 bisdesoxyisopodophyllamine
- 78178-34-4 desoxyisopodophyllamine
- 78178-37-7 O,N-diacetyldesoxyisopodophyllamine
- 78178-39-9 N,N-diethylcarbamoylbisdesoxyisopodophyllamine
- 78178-38-8 N-acetylbisdesoxyisopodophyllamine
- 78178-35-5 isobisdeoxypicropodophyllamine
- 78178-34-4 isodeoxypicropodophyllamine
- 78216-16-7 (5R)-7c-acetoxymethyl-6c-acetylamino-5r-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole
- 78216-17-8 N-acetyl-bis-desoxyisopicropodophyllamine
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α-apopodophyllamine
