2-(4-nitro-1H-pyrazol-1-yl)acetamide is a chemical compound with the molecular formula C5H6N4O3. It is a nitroarylpyrazole derivative and a potential inhibitor of the histone methyltransferase G9a. 2-(4-nitro-1H-pyrazol-1-yl)acetamide has been studied for its potential use in cancer therapy and has shown promising results in inhibiting the growth of cancer cells. Additionally, it has also been investigated for its role in the regulation of gene expression and cellular signaling. 2-(4-nitro-1H-pyrazol-1-yl)acetamide is synthesized by the reaction of 4-nitro-1H-pyrazole with chloroacetamide, and its properties and applications continue to be explored in the field of medicinal chemistry.
32407-64-0
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Basic information
- Product Name: 2-(4-nitro-1H-pyrazol-1-yl)acetamide
- Synonyms: 2-(4-nitro-1H-pyrazol-1-yl)acetamide
- CAS NO:32407-64-0
- Molecular Formula: C5H6N4O3
- Molecular Weight: 170.13
- EINECS: N/A
- Product Categories: N/A
- Mol File: 32407-64-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2-(4-nitro-1H-pyrazol-1-yl)acetamide(CAS DataBase Reference)
- NIST Chemistry Reference: 2-(4-nitro-1H-pyrazol-1-yl)acetamide(32407-64-0)
- EPA Substance Registry System: 2-(4-nitro-1H-pyrazol-1-yl)acetamide(32407-64-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 32407-64-0(Hazardous Substances Data)
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32407-64-0 Usage
Uses
Used in Cancer Therapy:2-(4-nitro-1H-pyrazol-1-yl)acetamide is used as an anticancer agent for its potential to inhibit the growth of cancer cells. It targets the histone methyltransferase G9a, which is involved in the regulation of gene expression and cellular signaling, and its inhibition may lead to the suppression of tumor growth and progression.
Used in Medicinal Chemistry Research:
2-(4-nitro-1H-pyrazol-1-yl)acetamide is used as a research compound in the field of medicinal chemistry. Its synthesis, properties, and potential applications are being explored to better understand its mechanism of action and to develop new therapeutic strategies for cancer treatment.
Used in Drug Development:
2-(4-nitro-1H-pyrazol-1-yl)acetamide is used as a lead compound in drug development for its potential as a histone methyltransferase inhibitor. Further research and optimization of its structure and properties may lead to the discovery of novel and effective anticancer drugs.
Used in Gene Expression and Cellular Signaling Studies:
2-(4-nitro-1H-pyrazol-1-yl)acetamide is used as a tool compound in studies investigating the role of histone methylation in gene expression and cellular signaling. Its ability to inhibit G9a may provide insights into the regulation of these processes and the development of targeted therapies for various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 32407-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,4,0 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.Calculate Digit Verification of CAS Registry Number 32407-64:
(7*3)+(6*2)+(5*4)+(4*0)+(3*7)+(2*6)+(1*4)=90
90 % 10 = 0
So 32407-64-0 is a valid CAS Registry Number.
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2-(4-nitro-1H-pyrazol-1-yl)acetamide
