324078-58-2Relevant academic research and scientific papers
Nickel-catalyzed allylation of lithium 1-alkynyl(trialkoxy)borates with 1,3-disubstituted allyl carbonates
Chen, Han,Deng, Min-Zhi
, p. 189 - 193 (2000)
The first Suzuki-type cross-coupling of alkynylborates with 1,3-disubstitued allyl carbonates was studies. It was found that nickel complexes readily catalyzed the reaction giving normal coupling products in good to excellent yields. The nickel complexes of dppe or dppen revealed a higher catalytic activity than that of NiCl2(PPh3)2 or NiCl2(dppf). This is a substrate-controlled reaction with high regioselectivity. The asymmetric cross-coupling reaction of alkynylborates with allyl carbonate enantioselectively produced an allyl substituted alkyne with 13%ee.
Catalytic decarboxylative sp-sp3 coupling
Rayabarapu, Dinesh Kumar,Tunge, Jon A.
, p. 13510 - 13511 (2007/10/03)
A palladium-catalyzed 1,4-enyne synthesis was developed based the decarboxylative coupling of acetylides with allyl electrophiles. Stereochemical studies have implicated palladium-allyl-acetylides as intermediates. Thus, decarboxylative metalation was established as an environmentally benign alternative to transmetalation from alkynyl tin reagents. Copyright
