32438-31-6

Basic information

• Product Name: (2,2-diethoxyethoxy)benzene
• Synonyms: Acetaldehyde,phenoxy-, diethyl acetal (6CI,8CI); Ethane, 1,1-diethoxy-2-phenoxy- (6CI);2-Phenoxyacetaldehyde diethyl acetal; NSC 67872; Phenoxyacetaldehyde diethylacetal
• CAS NO: 32438-31-6
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.28
• EINECS: 251-041-8
• Mol File: 32438-31-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 290.4°Cat760mmHg
• Flash Point: 96.4°C
• Appearance: /
• Density: 1.005g/cm³
• Vapor Pressure: 0.00361mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: (2,2-diethoxyethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-diethoxyethoxy)benzene(32438-31-6)
• EPA Substance Registry System: (2,2-diethoxyethoxy)benzene(32438-31-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 32438-31-6(Hazardous Substances Data)

Usage

General Description

(2,2-diethoxyethoxy)benzene is a chemical compound with the molecular formula C12H18O3. It is also known by the name "triethylene glycol monoethyl ether." This colorless, oily liquid is commonly used as a solvent in various industrial applications, such as in paint, varnish, and coating formulations. It is also used as a chemical intermediate in the production of other compounds. (2,2-diethoxyethoxy)benzene has a relatively low toxicity level and is considered to be non-toxic to humans at normal exposure levels. However, it may cause irritation to the skin and eyes upon contact. It is important to handle this chemical with caution and follow proper safety protocols when working with it.

InChI:InChI=1/C12H18O3/c1-3-13-12(14-4-2)10-15-11-8-6-5-7-9-11/h5-9,12H,3-4,10H2,1-2H3

Upstream product

• 621-62-5 chloroacetaldehyde diethyl acetal 
• 108-95-2 phenol 
• 64-17-5 ethanol 
• 139-02-6 sodium phenoxide 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 271-89-6 1-benzofurane 
• 38657-62-4 cis-1-ethoxy-2-phenoxy-ethylene 
• 38657-63-5 trans-1-ethoxy-2-phenoxy-ethylene 
• 2120-70-9 2-phenoxyethanal 
• 75933-70-9 4-phenoxy-trans-crotonic acid 
• 59931-42-9 2-(3,5-dimethylphenyl)benzofuran 
• 53390-12-8 2-(2'-chlorophenyl)benzo[b]furan 
• 65246-45-9 2-(3-chlorophenyl)benzo[b]furan 
• 92724-29-3 2‐m‐tolylbenzofuran 
• 19234-04-9 2-(p-methoxyphenyl)-benzo[b]furan 
• 62924-10-1 2-(2,4-dimethoxyphenyl)benzofuran 
• 787-64-4 2-(4-nitrophenyl)-1-benzofurane 
• 26870-34-8 2-(3’-methoxyphenyl)benzofuran 
• 1839-72-1 2-phenylbenzofuran 

Relevant articles and documents

Preparation method of 2,3-dihydrobenzofuran

The invention discloses a preparation method of 2,3-dihydrobenzofuran. The preparation method comprises the following steps: with phenol and 2-bromoacetaldehyde diethyl acetal as initial raw materials, carrying out condensing to obtain 2-phenoxyacetaldehyde diethyl acetal; carrying out cyclizing to obtain benzofuran; and finally, conducting hydrogenating to obtain 2,3-dihydrobenzofuran. The methodprovided by the invention can be used for preparing 2,3-dihydrobenzofuran, and has the advantages of easily available raw materials, mild reaction conditions, easy operation, good product quality, high yield, low cost, small environmental pollution and relatively high economic benefits.

Palladium-Catalyzed Regioselective C-2 Arylation of Benzofurans with N′-Acyl Arylhydrazines

A novel ligand-free palladium-catalyzed C-2 arylation of benzofurans has been developed using N′-acyl arylhydrazines as the coupling partners and TEMPO as an oxidant. This protocol features a wide functional-group tolerance and highly regioselective products with good to excellent yields.

Zeolite-catalyzed synthesis of 2,3-unsubstituted benzo[b]furans via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals

An efficient and environmentally benign heterogeneous catalytic process for the synthesis of 2,3-unsubstituted benzo[b]furans has been established via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals. By utilizing tin-exchanged H-β zeolite (Sn-β) as catalyst, a wide range of functionalized 2,3-unsubstituted benzo[b]furans could be prepared in good to excellent yields. The Sn-β zeolite catalyst also exhibited excellent shape selectivity on the cyclization of meta-substituted 2-aryloxyacetaldehyde acetals, and 6-substituted isomers were preferably formed up to 97% regio-selectivity. Moreover, Sn-β zeolite could be easily recovered and reused without any noticeable activity loss.