32452-45-2 Usage
Uses
Used in Organic Synthesis:
Trans-2,5-dimethylpiperidine is used as a building block in organic synthesis for its ability to contribute to the formation of complex organic molecules, facilitating the creation of a diverse range of chemical compounds.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, Trans-2,5-dimethylpiperidine is utilized as a key component in the synthesis of certain drugs, playing a crucial role in the development of new medications.
Used in Agrochemical Production:
TRANS-2,5-DIMETHYLPIPERIDINE also serves as a reagent in the production of specific agrochemicals, contributing to the development of products designed to enhance agricultural productivity and crop protection.
Used in Materials Science:
Trans-2,5-dimethylpiperidine has potential applications in materials science, where it may be employed to develop new materials with unique properties for various industrial uses.
Used in Catalyst Development:
Furthermore, this chemical is involved in the development of new catalysts, which are essential in accelerating chemical reactions and improving the efficiency of numerous industrial processes.
It is important to handle Trans-2,5-dimethylpiperidine with care due to its potential health and environmental risks if mismanaged. Proper safety measures should be implemented to mitigate any risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 32452-45-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,4,5 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 32452-45:
(7*3)+(6*2)+(5*4)+(4*5)+(3*2)+(2*4)+(1*5)=92
92 % 10 = 2
So 32452-45-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H15N/c1-6-3-4-7(2)8-5-6/h6-8H,3-5H2,1-2H3/t6-,7-/m1/s1
32452-45-2Relevant academic research and scientific papers
Oxidation of methylpiperidine derivatives with regard to chirality
M?hrle, Hans,Berkenkemper, Thomas
experimental part, p. 1514 - 1523 (2008/10/09)
When 2-(2-methyl-1-piperidinyl)ethanol derivatives 3a and 3b were dehydrogenated with Hg(II)-EDTA, an iminium function involving the tertiary a-carbon atom of the piperidine ring is formed regioselectively. Cyclization of these intermediates yielded diastereomeric mixtures of oxazolidines 7a and 7b, in solutions of which hydroxy-enamine species 8a/9a and 8b/9b, respectively, could be detected by NMR spectroscopy. A hydroxy-enamine derived from 7a could be trapped by cycloaddition to tetrazine 10. Protonation of the oxazolidines generated the iminium salts 6a/6b·X with loss of a chirality center. For prevention of different directions of ring dehydrogenation in the 2-(3-methyl-1-piperidinyl)ethanol compounds, the 6-position was blocked with two methyl groups. With amino alcohol 17, the isolation of one of the racemates in pure form was achieved, which by dehydrogenation produced a diastereoisomeric lactam mixture 18, as shown by NMR spectroscopy. Reaction of 2-(4-methyl-1-piperidinyl)ethanol 19 with Hg(II)-EDTA gave rise to a diastereomeric lactam mixture 21 in the ratio 60:40. From enantiomerically pure phenyloxiranes, the amino alcohols R(-)-19 and S(+)-19 became available. Their dehydrogenation under standardized conditions always showed a spreading range of isomeric lactams, which could not be separated.
