324522-59-0Relevant academic research and scientific papers
Synthesis of a polyhydroxylated tetrahydro-4H-1,2,3-triazolo[1,5-a]azepin, a higher homolog of 'nojiritriazole', and of a related C-disaccharide
Tezuka,Compain,Martin
, p. 1837 - 1839 (2007/10/03)
The first synthesis of a polyhydroxylated tetrahydro-4H-1,2,3-triazolo[1,5-a]azepin derivative ('homonojiritriazole' 7) and of the related C-disaccharide 11 has been achieved from the 5-azido-5-deoxy-D-glucofuranose derivative 4, by way of an acetylide chain-extension and an internal [1,3]-dipolar cycloaddition. Compound 7 was found to be a very weak inhibitor of E. coli α-galactosidase and of isomaltase (α-glucosidase) from baker's yeast.
