324753-53-9Relevant academic research and scientific papers
A silicon tether approach for diastereocontrol in radical addition to chiral hydrazones
Friestad, Gregory K.
, p. 1499 - 1501 (1999)
(formula presented) A radical carbon-carbon bond construction approach to chiral α-branched amines is presented. Stereocontrolled radical addition to chiral hydrazones can be achieved by virtue of conformational constraints imposed during cyclizations usi
A Silicon Tether Approach for Addition of Functionalized Radicals to Chiral α-Hydroxyhydrazones: Diastereoselective Additions of Hydroxymethyl and Vinyl Synthons
Friestad, Gregory K.,Massari, Sara E.
, p. 863 - 875 (2007/10/03)
Stereocontrolled additions of hydroxymethyl and vinyl groups to chiral α-hydroxyhydrazones can be achieved by radical cyclizations using bromomethyl or vinyl radical precursors tethered via a temporary silicon connection. Tin-mediated 5-exo radical cycliz
