32500-67-7Relevant academic research and scientific papers
Protonated alkylpyrazole ionic liquid and method using same for synthesizing cyclic carbonate
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Paragraph 0021; 0023, (2018/01/12)
The invention relates to protonated alkylpyrazole ionic liquid with a structural formula as shown in the description, wherein n is equal to 1, 2, 3 or 4, and X is Cl, Br or I. The invention further discloses a method for synthesizing cyclic carbonate by using the protonated alkylpyrazole ionic liquid; the protonated alkylpyrazole ionic liquid and an epoxy compound are added into a high-pressure reaction kettle according to a molar ratio of 1 : (25 to 300), CO2 is introduced until pressure is 1-3 MPa, and constant-temperature constant-pressure reaction is performed for 1-5 hours at a temperature of 100-150 DEG C, and post-treatment is performed after reaction is ended, thus obtaining the cyclic carbonate. The method solves the problems that CO2 activation is difficulty, a catalyst is dear, a poisonous organic solvent is used, a synthesis process is complex, reaction conditions are harsh and the like in an existing method. The advantages of simple synthesis process, high catalyst activity, environmental friendliness, low cost and the like are achieved.
NEW THIENOPYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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Page/Page column 132; 164, (2015/07/15)
Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R12, X, A and n are as defined in the description.
Synthesis of pinacol esters of 1-alkyl-1H-pyrazol-5-yl- and 1-alkyl-1H-pyrazol-4-ylboronic acids
Ivachtchenko, Alexandre V.,Kravchenko, Dmitry V.,Zheludeva, Valentina I.,Pershin, Dmitry G.
, p. 931 - 939 (2007/10/03)
Starting from 1H-pyrazol, a wide number of 1-alkyl-1H-pyrazol-4-yl and 1-alkyl-1H-pyrazol-5-ylboronic acids and their pinacol esters were synthesized and characterized. The key step in the described methodology is the regioselective lithiation of the pyrazole ring. The synthesized pinacolates are stable under prolonged storage and can be used as convenient reagents in organic synthesis.
