32529-50-3

Usage

Uses

Used in Pharmaceutical Synthesis:
1,3-Dioxolane,2-(5-bromo-2-furanyl)is used as a key intermediate in the synthesis of pharmaceuticals for its ability to react with other compounds to form new medicinal entities. Its unique structure allows for the creation of a variety of drug molecules with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 1,3-Dioxolane,2-(5-bromo-2-furanyl)is utilized as a precursor in the development of new pesticides and other agricultural chemicals. Its reactivity and structural features contribute to the design of effective and targeted agrochemicals.
Used as an Industrial Solvent:
1,3-Dioxolane,2-(5-bromo-2-furanyl)serves as a solvent in various industrial processes due to its ability to dissolve a wide range of substances. This makes it a versatile component in the manufacturing of different products across various industries.
Used in Organic Synthesis Research:
1,3-Dioxolane,2-(5-bromo-2-furanyl)is employed as a building block in organic synthesis research, where its potential to form new compounds is explored. Researchers and chemists leverage its properties to innovate and develop novel organic compounds for a range of applications.

Upstream product

• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 107-21-1 ethylene glycol 
• 873583-41-6 2-(4,5-dibromo-2-furanyl)-1,3-dioxolane 

Downstream Products

• 20005-42-9 5-(4-bromophenyl)-2-furancarboxyaldehyde 
• 1276045-91-0 5-(1,3-dioxolan-2-yl)furan-2-yl-(cyclohexyl)methanone 
• 1276045-88-5 3-(5-(1,3-dioxolan-2-yl)furan-2-yl)benzenamine 
• 1276045-84-1 4-(5-(1,3-dioxolan-2-yl)furan-2-yl)phenol 
• 1276045-79-4 2-(5-(3,4,5-trimethoxyphenyl)furan-2-yl)-1,3-dioxolane 

Relevant academic research and scientific papers

ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.

A selective synthesis of 4-bromo-2-furancarboxaldehyde and its pinacolborane derivative

A selective synthesis of ethylene acetal of 4-bromo-2-furancarboxaldehyde (4) and its pinacolborane derivative (5) is described. The synthesis was carried out using 2-furancarboxaldehyde (1) that was brominated to 4,5-dibromo-2- furancarboxaldehyde (2) in an emulsion of aluminum chloride and methylene chloride. The product was isolated, protected as ethylene acetal, and selectively debrominated to the ethylene acetal of 4-bromo-2-furancarboxaldehyde (4) in one step. This moiety was reacted with pinacolborane to give a reactive reagent of Suzuki coupling.

Gamma-hydroxy-2-(fluoroalkylaminocarbonyl)-1-piperazinepentanamides and uses thereof

γ-Hydroxy-2-(fluoroalkylaminocarbonyl)-1-piperazinepentanamide compounds are inhibitors of HIV protease and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described. These compounds are effective against HIV viral mutants which are resistant to HIV protease inhibitors currently used for treating AIDS and HIV infection.

Conjugated Macrocycles Related to the Porphyrins. Part 2. Further Synthetic and Spectroscopic Studies on Difuryl Analogs of the Oxophlorins

The synthesis of three difuryl analogs of the oxophlorins is described.In common with the tetrapyrrolic oxophlorins, these compounds favor the keto tautomers and little, if any, of the enol tautomers are present in neutral solutions.Unlike the tetrapyrrol