32541-19-8Relevant academic research and scientific papers
C-H activation dependent Pd-catalyzed carbonylative coupling of (hetero)aryl bromides and polyfluoroarenes
Lian, Zhong,Friis, Stig D.,Skrydstrup, Troels
, p. 1870 - 1873 (2015)
The carbonylative coupling of aryl and heteroaryl bromides with polyfluoroarenes via palladium-catalyzed C-H activation is presented. This transformation proceeds efficiently at moderate reaction temperatures and does not require strong base or reactive intermediates. A near stoichiometric amount of CO is sufficient and the methodology can thus be easily expanded to include the preparation of [13C]-acyl labeled benzopolyfluorophenones.
