32549-33-0

Basic information

• Product Name: 1-(4-CHLORO-PHENYL)-IMIDAZOLIDINE-2,4-DIONE
• Synonyms: 1-(4-CHLORO-PHENYL)-IMIDAZOLIDINE-2,4-DIONE
• CAS NO: 32549-33-0
• Molecular Formula: C₉H₇ClN₂O₂
• Molecular Weight: 210.61708
• Mol File: 32549-33-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 226-228 °C
• Appearance: /
• Density: 1.453g/cm³
• Refractive Index: 1.611
• PKA: 8.00±0.10(Predicted)
• CAS DataBase Reference: 1-(4-CHLORO-PHENYL)-IMIDAZOLIDINE-2,4-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLORO-PHENYL)-IMIDAZOLIDINE-2,4-DIONE(32549-33-0)
• EPA Substance Registry System: 1-(4-CHLORO-PHENYL)-IMIDAZOLIDINE-2,4-DIONE(32549-33-0)

Safety Data

• Hazardous Substances Data: 32549-33-0(Hazardous Substances Data)

Usage

General Description

1-(4-chloro-phenyl)-imidazolidine-2,4-dione is a chemical compound that belongs to the class of imidazolidine-2,4-dione derivatives. It contains a 4-chloro-phenyl group attached to the imidazolidine-2,4-dione moiety. 1-(4-CHLORO-PHENYL)-IMIDAZOLIDINE-2,4-DIONE has potential applications in the field of medicine and pharmaceuticals, as imidazolidine-2,4-dione derivatives have been studied for their various biological activities, including anticonvulsant, hypnotic, and sedative properties. Additionally, this compound may also have applications in the field of materials science, as imidazolidine-2,4-dione derivatives have been studied for their potential use as building blocks in the synthesis of novel materials.

InChI:InChI=1/C9H7ClN2O2/c10-6-1-3-7(4-2-6)12-5-8(13)11-9(12)14/h1-4H,5H2,(H,11,13,14)

Upstream product

• 6092-47-3 ethyl (chloroacetyl)carbamate 
• 106-47-8 4-chloro-aniline 
• 13014-48-7 4-chlorobenzoyl cyanide 
• 1345028-87-6 C₁₀H₉ClN₂O₂ 
• 79-11-8 chloroacetic acid 
• 57-13-6 urea 

Downstream Products

• 1317242-27-5 1-(4-chlorophenyl)-5-(thiiran-2-ylmethyl)imidazolidine-2,4-dione 
• 1317242-25-3 1-(4-chlorophenyl)-5-(oxiran-2-ylmethyl)imidazolidine-2,4-dione 
• 6212-33-5 2-(4-Chlorophenyl)glycine 
• 1314745-27-1 1-(4-chlorophenyl)-2,4-dichloro-1H-imidazole-5-carbaldehyde 
• 1314745-47-5 2-({[2,4-dichloro-1-(4-chlorophenyl)-1H-imidazol-5-yl]methylene}amino)ethanol 
• 1240969-74-7 2-piperidinyl-1-(4-chlorophenyl)-4-chloro-1H-imidazole-5-carbaldehyde 
• 1314745-42-0 2-isopentoxy-1-(4-chlorophenyl)-4-chloro-1H-imidazole-5-carbaldehyde 
• 1314745-35-1 2-azido-1-(4-chlorophenyl)-4-chloro-1H-imidazole-5-carbaldehyde 
• 188116-07-6 Imepitoin 

Relevant articles and documents

Preparation method for D, L-phenylglycine and analogue thereof

The invention provides a preparation method for D, L-phenylglycine and an analogue thereof. According to the method, benzaldehyde, an analogue thereof and hydrocyanic acid are adopted as raw materials and subjected to cyanidation reaction, and then 2-hydroxy-benzyl cyanide or 2-hydroxy-benzyl cyanide analogue (cyanohydrin for short) is generated. Cyanohydrin reacts with carbon dioxide and the aqueous solution of ammonia, and then 5-phenyl-hydantoin and an analogue thereof (hydantoin for short) are generated. hydantoin is successively subjected to steam stripping, alkaline hydrolysis, steam stripping, decolorization, neutralization, crystallization, washing, centrifuging, drying and the like to obtain D, L-phenylglycine and the analogue thereof. Compared with the prior art, the preparation method for D, L-phenylglycine and the analogue thereof can significantly and effectively reduce the pollution, and fewer inorganic salt by-products are generated. Meanwhile, the prepared D, L-phenylglycine and the analogue thereof are high in product yield and high in purity. Counted in benzaldehyde and the analogue thereof, the yield of D, L-phenylglycine and the analogue thereof is larger than or equal to 96%, and the product purity is larger than or equal to 99%. Meanwhile, the process flow is simple and feasible, so that the method is worthy of market popularization and application.

Synthesis of some oxa- and thiazolidine-1,3-diones and their oxiranyl and thiiranyl derivatives

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New compounds: synthesis of 1-aryl substituted hydantoins.

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