325490-26-4

Upstream product

• 325490-27-5 N-1-(1-cyclohexenyl)ethylphthalimide 
• 1003-64-1 ethylidenecyclohexane 
• 932-66-1 1-cyclohexenyl methyl ketone 
• 76888-38-5 1-(1-cyclohexenyl)ethanol 
• 863642-08-4 1-<1-(1-cyclohexen-1-yl)ethyl>-1,2-hydrazinedicarboxylic acid bis(2,2,2-trichloroethyl) ester 

Downstream Products

• 14299-68-4 3-(1-Cyclohex-1-enyl-ethylamino)-butyric acid 1-prop-2-ynyl-cyclohexyl ester 
• 1289142-94-4 (S)-N-(1-cyclohexenylethyl)benzamide 
• 1289142-68-2 (R)-N-(1-cyclohexenylethyl)benzamide 
• 132408-77-6 1-(1-acetamidoethyl)-1-cyclohexene 

Relevant academic research and scientific papers

Non-enzymatic acylative kinetic resolution of primary allylic amines

A non-enzymatic acetyl transfer-based kinetic resolution of primary allylic amines is reported. The process involves the use of (1S,2S)-1 in conjunction with a supported ammonium salt and affords the corresponding enantio-enriched N-acetylated allylic ami

A dual-catalysis/anion-binding approach to the kinetic resolution of allylic amines

Chemical equations presented. A dual-catalysis approach enables the small-molecule catalyzed kinetic resolution of allylic amines by acylation. By employing 2 mol % of each 4-(pyrrolidino)pyridine (PPY) and a readily available chiral hydrogen-bonding coca

Resolution of β-unsaturated amines with isopropylidene glycerol hydrogen phthalate

1-Phenyl-2-propenylamine 2, 1-phenyl-2-propinylamine 3, 1-(1-cyclohexenyl)ethylamine 4, (E)-2-ethylidenecyclohexylamine 5 and α-methylallylamine hydrochloride 6 were selected as candidates for resolution with isopropylidene glycerol hydrogen phthalate 1, previously described as an efficient resolving agent of 1-arylalkylamines. With only the exception of 5, all these substrates were resolved by (S)-1. In particular both the enantiomers of 2 and 3 were obtained in excellent yields and with very high enantiomeric excesses. The absolute configurations of non-racemic forms of 2, 3 and 4, not prepared before except those of 3, were established by correlation with the respective hydrogenation products. The enantiomeric excesses of all the resolved substrates were accurately determined by chiral HPLC analysis. The fact that 1 resolves 4 and 6 but not their saturated analogues and shows higher efficiency in resolving 2 and 3 than 1-phenylpropylamine indicates the positive influence of the presence of β-unsaturation on the resolvability of aminic substrates with such an acid. Copyright (C) 2000 Elsevier Science Ltd.