325491-81-4 Usage
General Description
4-(2-METHYLTHIAZOL-4-YL)BUTAN-1-AMINE, also known as Pevonedistat, is a chemical compound used in the development of pharmaceuticals. It belongs to the class of thiazole derivatives and is commonly used as a selective inhibitor of NEDD8-activating enzyme (NAE). This enzyme is involved in the process of protein degradation, making it an attractive target for cancer therapy. Pevonedistat has shown promise in preclinical studies for the treatment of various types of cancer, including solid tumors and hematologic malignancies. Its ability to inhibit NEDD8-activating enzyme makes it a potential candidate for combination therapy with other anti-cancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 325491-81-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,5,4,9 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 325491-81:
(8*3)+(7*2)+(6*5)+(5*4)+(4*9)+(3*1)+(2*8)+(1*1)=144
144 % 10 = 4
So 325491-81-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H14N2S/c1-7-10-8(6-11-7)4-2-3-5-9/h6H,2-5,9H2,1H3
