32562-61-1Relevant articles and documents
Isomeric monoacetylmono(1-hydroxyethyl)deuteroporphyrins: Syntheses, characterization, and use for the syntheses of regioselectively methyl- and vinyl-deuterated hemins
Shiau,Pandey,Ramaprasad,Dougherty,Smith
, p. 2190 - 2195 (1990)
Treatment of hematoporphyrin IX dimethyl ester (7) with tetrapropylammonium perruthenate (Pr(n)4N(RuO4) and N-methylmorpholine N-oxide affords a high yield of the separable monoacetylmono(1-hydroxyethyl)-deuteroporphyrin isomers 5 and 6. Proton NMR NOE experiments and chemical transformations involving specific individual deuteration at the 1- and 3-methyls and 2- and 4-vinyls are used to characterize the isomers.
Process For Preparing Porphyrin Derivatives, Such As Protoporphyrin (IX) And Synthesis Intermediates
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Page/Page column 13; 20, (2008/12/07)
The present invention relates to a process for preparing a porphyrin of formula (I), optionally in the form of a salt with an alkali metal and/or in the form of a metal complex: in which: R and R′ are as defined in claim 1, comprising: a step of condensation, in an acidic medium, between a dipyrromethane of formula (II): in which R′b is as defined above for (I), and a dipyrromethane of formula (III): in which R″ is as defined in claim 1, and also the compounds of formula (III).
A FACILE PORPHYRIN ESTERIFICATION / ETHERIFICATION PROCEDURE
Byrne, Christopher J.,Ward, A. David
, p. 1421 - 1424 (2007/10/02)
Porphyrin carboxylic acids and 1-hydroxyethyl groups can be rapidly esterified and etherified using alcohol/trialkyl orthoformate/strong acid mixtures; addition of water to the reagent permits esterification only.