32566-03-3

Upstream product

• 878133-05-2 N-(4-bromo-2-iodophenyl)-2,2,2-trifluoroacetamide 
• 1407182-05-1 C₁₆H₁₀BrF₃N₂O 

Downstream Products

• 1621887-31-7 2-(4-fluorophenyl)-5-(indolo[1,2-c]quinazolin-2-yl)-N-methyl-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide 
• 1621887-33-9 2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)-5-(5-(methylsulfonyl)-5,6-dihydroindolo[1,2-c]quinazolin-2-yl)benzofuran-3-carboxamide 

Relevant academic research and scientific papers

TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF HEPATITIS C

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

Palladium(II)-catalyzed cycloamidination via C(sp2)-H activation and isocyanide insertion

An efficient method for the synthesis of nitrogen heterocycles containing a cyclic amidine moiety has been developed. The process involves palladium-catalyzed C(sp2)-H activation and isocyanide insertion starting with readily accessible ortho-heteroarene-substituted aniline derivatives under mild conditions. Copyright