325705-80-4Relevant academic research and scientific papers
Oligonucleotide analogues with integrated bases and backbone: Part 13 - Synthesis and association of ethynylene-linked self-complementary dimers
Zhang, Xiaomin,Bernet, Bruno,Vasella, Andrea
, p. 2861 - 2917 (2007/10/03)
The self-complementary UA and AU dinucleotide analogues 41-45, 47, 48, and 51-60 were prepared by Sonogashira coupling of 6-iodouridines with C(5′)-ethynylated adenosines and of 8-iodoadenosines with C(5′)-ethynylated uridines. The dinucleotide analogues
The 5',6-oxomethylene transglycosidic tether for conformational restriction of pyrimidine ribonucleosides. Investigation of 6-formyl- and 6-(hydroxymethyl)uridine 5'-carboxaldehydes
Groziak, Michael P.,Lin, Ronghui
, p. 9885 - 9893 (2007/10/03)
In an effort to develop a new motif for the transglycosidic tethering of the pyrimidine nucleoside framework, the 2',3'-O-isopropylidenated and unprotected versions of 6-formyl- and 6-(hydroxymethyl)uridine 5'-carboxaldehyde were prepared and these were e
