325806-59-5

Basic information

• Product Name: C₁₈H₁₇NO₅S
• CAS NO: 325806-59-5
• Molecular Weight: 359.403
• Mol File: 325806-59-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₇NO₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₇NO₅S(325806-59-5)
• EPA Substance Registry System: C₁₈H₁₇NO₅S(325806-59-5)

Safety Data

• Hazardous Substances Data: 325806-59-5(Hazardous Substances Data)

Upstream product

• 108-31-6 maleic anhydride 
• 4815-37-6 ethyl 2-amino-5-methyl-4-phenylthiophene-3-carboxylate 

Relevant articles and documents

Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors

Secreted frizzled related protein-1 (sFRP-1) inhibitors have the potential to be used for the treatment of osteoporosis or other bone related disorders, since the level of sFRP-1 affects osteoblast apoptosis and proliferation. From high throughput screening, we have identified a class of iminooxothiazolidines as sFRP-1 inhibitors. Structure-activity relationships were established for various regions of the scaffold along with the biochemical characterization of this class to probe selectivity, binding and ex vivo activity.