325822-33-1Relevant academic research and scientific papers
Scouting human A3 adenosine receptor antagonist binding mode using a molecular simplification approach: From triazoloquinoxaline to a pyrimidine skeleton as a key study
Morizzo, Erika,Capelli, Francesca,Lenzi, Ombretta,Catarzi, Daniela,Varano, Flavia,Filacchioni, Guido,Vincenzi, Fabrizio,Varani, Katia,Borea, Pier Andrea,Colotta, Vittoria,Moro, Stefano
, p. 6596 - 6606 (2008/09/16)
The concept of molecular simplification as a drug design strategy to shorten synthetic routes, while keeping or enhancing the biological activity of the lead drug, has been applied to design new classes of human A3 adenosine receptor (AR) antag
