32585-52-7Relevant academic research and scientific papers
Derivative of Fascaplysin, preparation method and application
-
Paragraph 0017-0019; 0039-0040, (2018/04/28)
The invention discloses a derivative of Fascaplysin, preparation thereof and application of derivative of Fascaplysin in drugs. The general formula of the derivative of Fascaplysin is shown in formula(I), the compound can be applied to preparation of drugs for preventing and treating diseases related to a cyclin dependent kinase CDK4 inhibitor and anti-cancer drugs. The drug action of the CDK4 inhibitor is retained, the yield of the compound is high, the compound is relatively stable in air, and water solubility is good. The derivative of Fascaplysin has the advantages of simplicity in operation, simplicity and convenience in preparation method and low production cost.
