325850-38-2Relevant academic research and scientific papers
Palladium-Catalyzed One-Pot Synthesis of 5-(1-Arylvinyl)-1H-benzimidazoles: Overcoming the Limitation of Acetamide Partners
Naret, Timothée,Retailleau, Pascal,Bignon, Jér?me,Brion, Jean-Daniel,Alami, Mouad,Hamze, Abdallah
supporting information, p. 1833 - 1847 (2016/06/09)
A new one-pot palladium-catalyzed process between N-tosylhydrazones, N-(dihalophenyl)-imidates, and amines was designed. This reaction involves Barluenga cross-coupling and N-arylation followed by cyclization to produce functionalized benzimidazoles. Duri
Csp2-N bond formation via ligand-free Pd-catalyzed oxidative coupling reaction of N -tosylhydrazones and indole derivatives
Roche, Maxime,Frison, Gilles,Brion, Jean-Daniel,Provot, Olivier,Hamze, Abdallah,Alami, Mouad
, p. 8485 - 8495 (2013/09/24)
In a fresh approach to the synthesis of N-vinylazoles, a ligand-free palladium catalytic system was found to promote the Csp2-N bond-forming reaction utilizing N-tosylhydrazones and N-H azoles. This process shows functional group tolerance; di-, tri-, and tetrasubstituted N-vinylazoles were obtained in high yields. Under the optimized conditions, the reaction proceeds with high stereoselectivity depending on the nature of the coupling partners.
