3260-78-4

Basic information

• Product Name: 5-BROMO-BENZOFURAN-3-ONE
• Synonyms: 6-CHLORO-BENZOFURAN-3-ONE;5-BROMO-BENZOFURAN-3-ONE;3(2H)-BENZOFURANONE, 5-BROMO-;6-Chloro-3(2H)-benzofuranone;6-Bromo-3-Benzofuranone;5-bromobenzofuran-3(2H)-one;3(2H)-Benzofuranone, 6-chloro-;6-BROMOBENZOFURAN-3(2H)-ONE
• CAS NO: 3260-78-4
• Molecular Formula: C₈H₅ClO₂
• Molecular Weight: 213.03
• Mol File: 3260-78-4.mol
• Article Data: 16

Chemical Properties

• Melting Point: 123-123.5 °C
• Boiling Point: 304.337 °C at 760 mmHg
• Flash Point: 145.621 °C
• Appearance: /
• Density: 1.428 g/cm³
• Refractive Index: 1.601
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 5-BROMO-BENZOFURAN-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-BENZOFURAN-3-ONE(3260-78-4)
• EPA Substance Registry System: 5-BROMO-BENZOFURAN-3-ONE(3260-78-4)

Safety Data

• Hazardous Substances Data: 3260-78-4(Hazardous Substances Data)

Usage

Chemical Properties

Orange Solid

InChI:InChI=1/C8H5ClO2/c9-5-1-2-6-7(10)4-11-8(6)3-5/h1-3H,4H2

Upstream product

• 401622-26-2 2-(carboxymethoxy)-4-chloro-benzoic acid 
• 872191-28-1 6-chlorobenzofuran-3-yl acetate 
• 2420-26-0 4-chlorosalicylaldehyde 
• 36739-98-7 2-Hydroxy-4-chlorphenylacetylen 
• 5106-98-9 4-chlorosalicylic acid 
• 22717-55-1 methyl 4-chloro-2-hydroxybenzoate 
• 6921-66-0 4-chloro-2-hydroxy acetophenone 
• 157068-00-3 2-bromo-1-(4-chloro-2-hydroxyphenyl)ethan-1-one 
• 796851-66-6 methyl 4-chloro-2-(2-ethoxy-2-oxoethoxy)benzoate 

Downstream Products

• 139313-79-4 (6-Chloro-benzofuran-3-yl)-acetonitrile 
• 857062-41-0 2-bromo-6-chloro-benzofuran-3-one 
• 82156-62-5 ethyl (6-chloro-1-benzofuran-3-yl)acetate 
• 960064-24-8 C₁₃H₈ClN₃O₄ 
• 960064-08-8 C₁₃H₈ClN₃O₄ 
• 1154740-97-2 C₈H₇ClO₂ 
• 1387635-10-0 6-chloro-2-(6-chlorobenzofuran-3-yl)-3-ethoxybenzofuran 

Relevant articles and documents

A Hg(OTf)2-Catalyzed Enolate Umpolung Reaction Enables the Synthesis of Coumaran-3-ones and Indolin-3-ones

The potential of mercury catalysis has been extended to the arena of enolate umpolung reactions for the first time by the generation of enolonium species via Hg(OTf)2-catalyzed N-oxide addition to alkynes. The enolonium species formed can undergo intramolecular nucleophilic attack by hydroxyl or amino groups, leading to the synthesis of various coumaran-3-ones and indolin-3-ones.

(AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES

Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.

Practical, modular, and general synthesis of 3-coumaranones through gold-catalyzed intermolecular alkyne oxidation strategy

A gold-catalyzed intermolecular alkyne oxidation for the preparation of 3-coumaranones has been developed. Using 8-isopropylquinoline N-oxides as oxidants, the reactions of o-ethynylanisoles afford versatile 3-coumaranones in moderate to good isolated yields. The synthetic utility of this chemistry is also indicated by the synthesis of the natural product sulfuretin.