326487-39-2

Basic information

• Product Name: (4S,5S)-4-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-(4-methoxy-phenyl)-2-methyl-4,5-dihydro-furan-3-carboxylic acid isopropyl ester
• CAS NO: 326487-39-2
• Molecular Weight: 479.53
• Mol File: 326487-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5S)-4-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-(4-methoxy-phenyl)-2-methyl-4,5-dihydro-furan-3-carboxylic acid isopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-(4-methoxy-phenyl)-2-methyl-4,5-dihydro-furan-3-carboxylic acid isopropyl ester(326487-39-2)
• EPA Substance Registry System: (4S,5S)-4-((S)-4-Benzyl-2-oxo-oxazolidine-3-carbonyl)-5-(4-methoxy-phenyl)-2-methyl-4,5-dihydro-furan-3-carboxylic acid isopropyl ester(326487-39-2)

Safety Data

• Hazardous Substances Data: 326487-39-2(Hazardous Substances Data)

Upstream product

• 542-08-5 isopropyl acetoacetate 
• 154006-98-1 (4S)-3-<(2E)-3-(4-methoxyphenyl)propenoyl>-4-phenylmethyl-1,3-oxazolidin-2-one 
• 34446-64-5 (E)-3-(4-methoxyphenyl)propenoyl chloride 
• 101711-90-4 (S)-4-benzyl-2-oxazolidinone lithium salt 

Relevant articles and documents

Asymmetric Mn(III)-based radical synthesis of functionalized 2,3-dihydrofurans

The oxidative radical addition of alkyl acetoacetates to p-methoxycinnamoyl oxazolidinones promoted by Mn(III) has been studied. It only gives trans-disubstituted 2,3-dihydrofurans, with d.r. ranging from 2:1 to 9:1, depending on the substituent of the chiral auxiliary. After chromatographic separation of the two diastereomers, the oxazolidinone can be removed to afford enantiopure dihydrofuranyl esters in good overall yield. (C) 2000 Elsevier Science Ltd.