2-Azaniumylethyl (2R)-2,3-bis[(2H27)tetradecanoyloxy]propyl phosphate, also known as cardiolipin (CL), is a unique phospholipid found in the inner mitochondrial membrane that plays a critical role in maintaining bioenergetic functions and mitochondrial dynamics. It is composed of four fatty acyl chains and two phosphate groups, giving it a dimeric structure. CL is involved in various mitochondrial processes, including electron transport chain function, protein import, and apoptosis regulation. Its unique structure and functions make it an essential component for maintaining mitochondrial function and cell survival. Dysregulation of CL metabolism has been implicated in various human diseases, including heart failure, diabetes, and neurodegenerative disorders.
326495-41-4
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Basic information
- Product Name: 1,2-DIMYRISTOYL-D54-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
- Synonyms: 1,2-DIMYRISTOYL-D54-SN-GLYCERO-3-PHOSPHOETHANOLAMINE;14:0 D54 PE;14:0 PE-d54;NEZDNQCXEZDCBI-QHDWWDETSA-N
- CAS NO:326495-41-4
- Molecular Formula: C33H12D54NO8P
- Molecular Weight: 690.19
- EINECS: N/A
- Product Categories: N/A
- Mol File: 326495-41-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1,2-DIMYRISTOYL-D54-SN-GLYCERO-3-PHOSPHOETHANOLAMINE(CAS DataBase Reference)
- NIST Chemistry Reference: 1,2-DIMYRISTOYL-D54-SN-GLYCERO-3-PHOSPHOETHANOLAMINE(326495-41-4)
- EPA Substance Registry System: 1,2-DIMYRISTOYL-D54-SN-GLYCERO-3-PHOSPHOETHANOLAMINE(326495-41-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 326495-41-4(Hazardous Substances Data)
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326495-41-4 Usage
Uses
Used in Pharmaceutical Industry:2-Azaniumylethyl (2R)-2,3-bis[(2H27)tetradecanoyloxy]propyl phosphate is used as a therapeutic target for the treatment of various human diseases, such as heart failure, diabetes, and neurodegenerative disorders. Its dysregulation has been implicated in these diseases, making it a promising candidate for drug development.
Used in Biomedical Research:
2-Azaniumylethyl (2R)-2,3-bis[(2H27)tetradecanoyloxy]propyl phosphate is used as a research tool to study mitochondrial function and dynamics, as well as the role of CL in various cellular processes. Understanding its role in these processes can help in the development of new therapeutic strategies for diseases associated with mitochondrial dysfunction.
Used in Drug Delivery Systems:
2-Azaniumylethyl (2R)-2,3-bis[(2H27)tetradecanoyloxy]propyl phosphate can be used as a component in drug delivery systems to target mitochondria-specifically. This can help in the development of targeted therapies for diseases associated with mitochondrial dysfunction, improving the efficacy and reducing the side effects of treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 326495-41-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,6,4,9 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.Calculate Digit Verification of CAS Registry Number 326495-41:
(8*3)+(7*2)+(6*6)+(5*4)+(4*9)+(3*5)+(2*4)+(1*1)=154
154 % 10 = 4
So 326495-41-4 is a valid CAS Registry Number.
326495-41-4Upstream product
326495-41-4Downstream Products
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1,2-DIMYRISTOYL-D54-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
