326599-48-8

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 326598-95-2 (1R,3S,4S,5R)-5-acetoxy-3-hydroxy-4-methyl-1-(methoxycarbonyl)cyclohexane 

Downstream Products

• 607353-60-6 (4S,6R)-1-methyl-6-(4'-nitrobenzoyloxy)-4-(methoxycarbonyl)cyclohexene 
• 607353-61-7 (4S,6R)-6-hydroxy-1-methyl-4-(methoxycarbonyl)cyclohexene 
• 607353-59-3 (4S,6S)-6-hydroxy-1-methyl-4-(methoxycarbonyl)cyclohexene 
• 38235-58-4 trans-sobrerol 
• 326599-68-2 methyl (1S,5S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-3-cyclohexene-1-carboxylate 
• 758719-57-2 (1R,3S,4S,5R)-3-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-5-(4-nitro-benzenesulfonyloxy)-cyclohexanecarboxylic acid methyl ester 
• 758719-58-3 (1S,3S,4R,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-5-propionyloxy-cyclohexanecarboxylic acid methyl ester 
• 758719-60-7 (1R,3S,4R,5R)-3-(tert-Butyl-diphenyl-silanyloxy)-5-methanesulfonyloxy-4-methyl-cyclohexanecarboxylic acid methyl ester 
• 326599-70-6 (1R,3S,4S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-5-methanesulfonyloxy-4-methyl-cyclohexanecarboxylic acid methyl ester 
• 758719-59-4 methyl (1S,3S,4S,5R)-3-(tert-butyldiphenylsilyloxy)-5-hydroxy-4-methylcyclohexane-1-carboxylate 
• 326599-69-3 methyl (1S,3S,4R,5S)-3-(tert-butyldiphenylsilyloxy)-5-hydroxy-4-methylcyclohexane-1-carboxylate 
• 758719-61-8 methyl (1R,3S,4S,5R)-3-(tert-butyldiphenylsilyloxy)-4-methylbicyclo[3.1.0]hexane-1-carboxylate 
• 758719-63-0 methyl (1S,3S,4S,5S)-3-(tert-butyldiphenylsilyloxy)-4-methylbicyclo[3.1.0]hexane-1-carboxylate 
• 326599-72-8 methyl (1R,3S,4R,5R)-3-(tert-butyldiphenylsilyloxy)-4-methylbicyclo[3.1.0]hexane-1-carboxylate 

Relevant academic research and scientific papers

Synthesis of 2-methyl and ethyl-substituted 19-nor-1α,25- dihydroxyvitamin D3 analogues via the cyclovitamin strategy

The synthesis of several 19-nor-2-alkyl-1α,25-dihydroxyvitamin D 3 analogues (5-14) is described following the cyclovitamin strategy. Starting from all-cis methyl 3,5-dihydroxy-4-alkyl-1-cyclohexanecarboxylate (29), the eight stereoisomeric A-r

A convenient, large scale synthesis of trans-(+)-sobrerol

A convenient and highly efficient synthesis of optically pure trans(+)-sobrerol (1), starting from methyl 3,5-dihydroxy-4-methyl benzoate 2 in 8 steps with overall yield 26%, is reported. The key intermediate 4 is prepared in remarkably high yield by selectively esterification of 3 using lipase as catalyst. A critical step to stereoselectively inverse the configuration of 7 is realized under Mistunobu conditions.