326852-28-2Relevant academic research and scientific papers
Non-peptidic, non-prenylic bisubstrate farnesyltransferase inhibitors. Effect of a carboxyl group at the central group on farnesyltransferase inhibitory activity
Schlitzer,Sattler
, p. 507 - 512 (2007/10/03)
We recently described non-peptidic, non-prenylic bisubstrate analogues as novel farnesyltransferase inhibitors comprising three modules - a farnesyl-mimetic, a linker and an AAX-peptidomimetic substructure. In this study, we replaced the originally used β
