326909-19-7Relevant academic research and scientific papers
Activated nitriles in heterocyclic chemistry: Facile synthesis and antimicrobial activity of some pyrimidine, pyrazolopyrimidine and pyrazolotriazine derivatives containing sulfonarnido moiety
Ammar,Saleh,Micky,Abbas,El-Gaby
, p. 2203 - 2211 (2007/10/03)
Novel pyrimidine, pyrazolopyrimidine and pyrazolotriazine derivatives containing sulfonyl moiety have been prepared using 4-(piperidin-1-sulfonyl) phenyl hydrazone 2 as a starting material. The antimicrobial activity of the prepared compounds is discussed
Novel synthesis and antimicrobial investigation of pyrazolo[1,5-a] pyrimidine and pyrazolotriazine containing piperidinyl sulfone moiety
Saleh,Ammar,Micky,Abbas,El-Gaby
, p. 2195 - 2202 (2007/10/03)
Diazonium salts of sulfones 1a,b are coupled with malononitrile to yield hydrazones 2a,b. Refluxing of the hydrazones 2a,b with hydrazine hydrate in ethanol furnished the aminopyrazoles 3a,b. The behaviour of aminopyrazole 3a towards some electrophilic re
