327-02-6

Basic information

• Product Name: 1H-IMIDAZO[4,5-C]PYRIDAZINE
• Synonyms: 1H-IMIDAZO[4,5-C]PYRIDAZINE
• CAS NO: 327-02-6
• Molecular Formula: C₅H₄N₄
• Molecular Weight: 0
• Mol File: 327-02-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-IMIDAZO[4,5-C]PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-IMIDAZO[4,5-C]PYRIDAZINE(327-02-6)
• EPA Substance Registry System: 1H-IMIDAZO[4,5-C]PYRIDAZINE(327-02-6)

Safety Data

• Hazardous Substances Data: 327-02-6(Hazardous Substances Data)

Upstream product

• 210042-88-9 C₂₁H₃₄N₈O₄SSi 
• 210042-87-8 2-(tert-Butyl-dimethyl-silanyl)-6,8-dioxo-7-phenyl-4,5,7,8-tetrahydro-6H-1,3,5a,7,8a-pentaaza-as-indacene-3-sulfonic acid dimethylamide 
• 210042-86-7 2-(tert-Butyl-dimethyl-silanyl)-6,8-dioxo-7-phenyl-5,7,8,8b-tetrahydro-6H-1,3,5a,7,8a-pentaaza-as-indacene-3-sulfonic acid dimethylamide 
• 210042-85-6 2-(tert-Butyl-dimethyl-silanyl)-5-vinyl-imidazole-1-sulfonic acid dimethylamide 
• 210042-90-3 C₁₅H₂₀N₈O₄S 

Relevant articles and documents

An efficient hetero Diels-Alder approach to imidazo[4,5-c]pyridazines as purine analogues

A general approach to 3-deaza-6-azapurine by a hetero Diels-Alder reaction is described. Reaction of sulfonamide protected 5-vinylimidazole with 4-phenyl-1,2,4-triazoline-3,5-dione in methanol gave the Diels-Alder adduct 8 in 85% yield. Deprotection of the resulting N-phenyltriazole was efficiently accomplished by ring opening with hydrazine followed by heating in DMSO. The completely deprotected and aromatized purine analogue 1 was obtained directly from this one-pot reaction in 48% yield.