32701-16-9Relevant academic research and scientific papers
Benzo[4,5]imidazo[2,1-b]quinazolin-12-ones and benzo[4,5]imidazo[1,2-a]pyrido[2,3-d]pyrimidin-5-ones by a sequential N-acylation-SNAr reaction
Gnanasekaran, Krishna Kumar,Muddala, Nagendra Prasad,Bunce, Richard A.
, p. 7180 - 7183 (2015/12/12)
An efficient synthesis of benzo[4.5]imidazo[2,1-b]quinazolin-12-ones and benzo[4,5]imidazo[1,2-a]pyrido[2,3-d]pyrimidin-5-ones is reported from the reaction of 2-aminobenzimidazole with 2-haloaroyl chlorides. The reaction takes advantage of the 1,3-dispos
Immunosuppressants
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, (2008/06/13)
Benzimidazo[2,1-b]quinazolin-12(6H)ones, immunosuppressives and agents for treatment of auto-immune diseases, are prepared via (1) reacting a 2-chlorobenzimidazole with an anthranilic acid or ester; (2) reacting a 2-aminobenzimidazole with an anthranilic acid or ester in the presence of trifluoroacetic acid or (3) reacting a 2-methylmercaptobenzimidazole with an anthraniloyl halide hydrohalide.
