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327056-62-2

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327056-62-2 Usage

General Description

2-Cyano-5-fluoropyridine is a chemical compound with the molecular formula C6H3FN2. It is a colorless to light yellow liquid with a faint odor. This chemical is mainly used as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. It is also used as a building block in organic synthesis for the preparation of a variety of chemical compounds. 2-Cyano-5-fluoropyridine is considered to be a hazardous chemical and should be handled and used with proper safety precautions as it can cause irritation to the skin, eyes, and respiratory system upon exposure.

Check Digit Verification of cas no

The CAS Registry Mumber 327056-62-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,7,0,5 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 327056-62:
(8*3)+(7*2)+(6*7)+(5*0)+(4*5)+(3*6)+(2*6)+(1*2)=132
132 % 10 = 2
So 327056-62-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H3FN2/c7-5-1-2-6(3-8)9-4-5/h1-2,4H

327056-62-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Alfa Aesar

  • (H25956)  2-Cyano-5-fluoropyridine, 98+%   

  • 327056-62-2

  • 1g

  • 512.0CNY

  • Detail
  • Alfa Aesar

  • (H25956)  2-Cyano-5-fluoropyridine, 98+%   

  • 327056-62-2

  • 5g

  • 1571.0CNY

  • Detail
  • Alfa Aesar

  • (H25956)  2-Cyano-5-fluoropyridine, 98+%   

  • 327056-62-2

  • 25g

  • 4854.0CNY

  • Detail
  • Aldrich

  • (703982)  2-Cyano-5-fluoropyridine  97%

  • 327056-62-2

  • 703982-1G

  • 575.64CNY

  • Detail
  • Aldrich

  • (703982)  2-Cyano-5-fluoropyridine  97%

  • 327056-62-2

  • 703982-5G

  • 1,931.67CNY

  • Detail

327056-62-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-fluoropyridine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names 5-FLUORO-2-CYANOPYRIDINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:327056-62-2 SDS

327056-62-2Relevant articles and documents

An improved Balz-Schiemann reaction enabled by ionic liquids and continuous processing

Snead, David R.,Lévesque, Fran?ois,Morris, William J.,Naber, John R.

, p. 4261 - 4265 (2019/05/24)

A Balz-Schiemann reaction was developed to convert 2-cyano-5-aminopyridine to 2-cyano-5-fluoropyridine. The use of an ionic liquid (1-butyl-3-methylimidazolium tetrafluoroborate, BMIMBF4) as a solvent was found to be critical in achieving high assay yields and high selectivity for the fluorination vs. protonation. A process was developed to recycle and reuse the ionic liquid enabling its cost-effective use as a solvent. Finally, the optimal conditions were demonstrated under as a continuous process to address process safety risks associated with diazonium intermediates and the product was used to access a key intermediate in the synthesis of β-amyloid cleaving enzyme 1 inhibitor, verubecestat.

Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists

-

, (2008/06/13)

The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.

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