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1-Iodo-2-methoxynaphthalene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

32721-21-4

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32721-21-4 Usage

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 4081, 1996 DOI: 10.1016/0040-4039(96)00738-1

Check Digit Verification of cas no

The CAS Registry Mumber 32721-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,2 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32721-21:
(7*3)+(6*2)+(5*7)+(4*2)+(3*1)+(2*2)+(1*1)=84
84 % 10 = 4
So 32721-21-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H9IO/c1-13-10-7-6-8-4-2-3-5-9(8)11(10)12/h2-7H,1H3

32721-21-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Iodo-2-methoxynaphthalene

1.2 Other means of identification

Product number -
Other names 1-iodo-2-methoxymethylnaphthalene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32721-21-4 SDS

32721-21-4Relevant academic research and scientific papers

I2-promoted selective oxidative cross-coupling/annulation of 2-naphthols with methyl ketones: A strategy to build naphtho[2,1- b ]furan-1(2 H)-ones with a quaternary center

Gao, Qinghe,Wu, Xia,Liu, Shan,Wu, Anxin

supporting information, p. 1732 - 1735 (2014/04/17)

A highly efficient and selective molecular iodine-promoted oxidative cross-coupling/annulation between 2-naphthols and methyl ketones has been realized. The reaction successfully constructed a new quaternary carbon center within 3(2H)-furanones. Our synth

An aluminum ate base: Its design, structure, function, and reaction mechanism

Naka, Hiroshi,Uchiyama, Masanobu,Matsumoto, Yotaro,Wheatley, Andrew E. H.,McPartlin, Mary,Morey, James V.,Kondo, Yoshinori

, p. 1921 - 1930 (2007/10/03)

An aluminum ate base, i-Bu3Al(TMP)Li, has been designed and developed for regio- and chemoselective direct generation of functionalized aromatic aluminum compounds. Direct alumination followed by electrophilic trapping with I2, Cu/Pd-catalyzed C-C bond formation, or direct oxidation with molecular O2 proved to be a powerful tool for the preparation of 1,2- or 1,2,3-multisubstituted aromatic compounds. This deprotonative alumination using i-Bu3Al(TMP)Li was found to be effective in aliphatic chemistry as well, enabling regio- and chemoselective addition of functionalized allylic ethers and carbamates to aliphatic and aromatic aldehydes. A combined multinuclear NMR spectroscopy, X-ray crystallography, and theoretical study showed that the aluminum ate base is a Li/Al bimetallic complex bridged by the nitrogen atom of TMP and the α-carbon of an i-Bu ligand and that the Li exclusively serves as a recognition point for electronegative functional groups or coordinative solvents. The mechanism of directed ortho alumination reaction of functionalized aromatic compounds has been studied by NMR and in situ FT-IR spectroscopy, X-ray analysis, and DFT calculation. It has been found that the reaction proceeds with facile formation of an initial adduct of the base and aromatic, followed by deprotonative formation of the functionalized aromatic aluminum compound. Deprotonation by the TMP ligand rather than the isobutyl ligand was suggested and reasoned by means of spectroscopic and theoretical study. The remarkable regioselectivity of the ortho alumination reaction was explained by a coordinative approximation effect between the functional groups and the counter Li+ ion, enabling stable initial complex formation and creation of a less strained transition state structure.

Effective and regioselective iodination of arenes using iron(III) nitrate in the presence of tungstophosphoric acid

Jafarzadeh, Mohammad,Amani, Kamal,Nikpour, Farzad

, p. 1808 - 1811 (2007/10/03)

An easy, cheap, and effective method for iodination of various aromatic compounds takes place with molecular iodine and iron nitrate nonahydrate as the oxidant in the presence of a catalytic amount of tungstophosphoric acid in dichloromethane, with good yield and high regioselectivity under very mild conditions.

2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof

-

, (2008/06/13)

New compounds, 2-(6'-methoxynaphth-2'-yl)propylene oxide, 2-(6'-methoxynaphth-2'-yl)propionaldoxime, 2-hydroxy-2-(6'-methoxynaphth-2'-yl)-propionitrile, 2-(6'methoxynaphth-2'-yl)acrylonitrile, 2-(6'-methoxynaphth-2'-yl)acrylic acid, the corresponding 5'-halo compounds and 2-(5'-halo-6'-methoxynaphth-2'-yl)propionaldehyde are useful intermediates in producing 2-(6'-methoxynaphth-2'-yl)propionic acid and the corresponding 5'-halo acids from 6-methoxy-2-acetylnaphthalene and the corresponding 5-halo compounds. The 2-propionic acids are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. The 2-propionaldehydes, obtained from the 2-acetyl compounds by way of the 2-propylene oxide, can be converted directly to the 2-propionic acids by way of the 2-propionaldoximes and the 2-propionitriles or more directly by Jones oxidation. Alternatively the 2-acrylonitriles, obtained from the 2-acetyl compounds by way of the 2-hydroxy-2-propionitrile, can be converted to the 2-propionic acid by way of the 2-acrylic acid or 2-propionitrile.

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