32739-28-9Relevant academic research and scientific papers
Biosynthesis of the indolizidine alkaloid cyclizidine: incorporation of singly and doubly labelled precursors
Leeper, Finian J.,Shaw, Susan E.,Satish, Padma
, p. 131 - 141 (2007/10/02)
Incorporation of CH313C18O2Na and CD3CH213CO2Na into the indolizidine alkaloid cyclizidine 1, produced by Streptomyces species NCIB 11649, shows that the oxygen attached to C-2 is derived intact from acetate and that the cyclopropyl ring is derived from a single intact propionate unit.However, the level and stereochemistry of the incorporation of deuteriated sodium propionate indicates that it undergoes unexpected modification during incorporation into the cyclopropyl ring.
