32741-27-8Relevant academic research and scientific papers
Cycloacylation of chloro-substituted hydroquinone dimethyl ethers with dichloromaleic anhydride
Novikov,Balaneva,Shestak,Anufriev, V. Ph.,Glazunov
, p. 993 - 1003 (2016)
Under the drastic conditions of Zahn—Ochwat cycloacylation of 2-chloroand 2,3-dichlorohydroquinones with dichloromaleic anhydride (a melt of anhydrous AlCl3 and NaCl, 185—195 °C), the substrates undergo various degrees of disproportionation, which reduces the yields of the target triand tetrachloronaphthazarins. Quantum chemical calculations showed that the cycloacylation in question proceeds as a double aromatic electrophilic substitution of the vicinal protons with the corresponding oxocarbenium ions (acylium cations).
