32755-44-5

Usage

InChI:InChI=1/C14H17NO2/c1-14(2,3)17-13(16)12(15-4)10-11-8-6-5-7-9-11/h5-9,12H,10H2,1-3H3

Upstream product

• 61900-41-2 N-Formylphenylalanin-tert-butylester 
• 16367-71-8 t-butyl (RS)-phenylalaninate 
• 150-30-1 Phenylalanine 

Downstream Products

• 1261037-19-7 tri-tert-butyl 3-benzyl-1H-1,2,4-triazole-1,2,3(3H)-tricarboxylate 
• 1261037-18-6 3-tert-butyl 1,2-diisopropyl 3-benzyl-1H-1,2,4-triazole-1,2,3(3H)-tricarboxylate 
• 1261037-20-0 1,2-dibenzyl 3-tert-butyl 3-benzyl-1H-1,2,4-triazole-1,2,3(3H)-tricarboxylate 
• 1261037-35-7 5-tert-butyl 1-ethyl 5-benzyl-1H-1,2,4-triazole-1,5(2H,5H)-dicarboxylate 
• 1261037-36-8 5-tert-butyl 1-isopropyl 5-benzyl-1H-1,2,4-triazole-1,5(2H,5H)-dicarboxylate 
• 1261037-15-3 3-tert-butyl 1,2-diethyl 3-benzyl-1H-1,2,4-triazole-1,2,3(3H)-tricarboxylate 

Relevant academic research and scientific papers

Enantioselective synthesis of 1,2,4-triazolines by chiral iron(ii)-complex catalyzed cyclization of α-isocyano esters and azodicarboxylates

Enantioselective cyclization of α-isocyano esters with azodicarboxylates catalyzed by FeII-N,N′-dioxide complexes has been developed. Under mild conditions, a variety of 1,2,4-triazoline derivatives was obtained in high yields and enantioselectivities.

Synthesis of 1,2,4-triazolines: Base-catalyzed hydrazination/cyclization cascade of α-isocyano esters and amides

A convenient, efficient synthesis of 1,2,4-triazolines from α-isocyano esters/amides and azodicarboxylates is presented. The developed reaction cascade is based on a base-catalyzed hydrazination-type reaction followed by a subsequent cyclization providing