32776-15-1Relevant academic research and scientific papers
Pd(0)-Catalyzed Conjugate Addition of Benzylzinc Chlorides to α,β-Enones in An Atmosphere of Carbon Monoxide: Preparation of 1,4-Diketones
Yuguchi, Motoki,Tokuda, Masao,Orito, Kazuhiko
, p. 908 - 914 (2007/10/03)
Pd(0)-catalyzed conjugate addition of benzylzine chloride to methyl vinyl ketone in the presence of chlorotrimethylsilane and lithium chloride in an atmosphere of carbon monoxide at room temperature afforded 1-phenyl-2,5-hexanedione monosilyl enol ether. In this catalytic carbonylation, four components are connected in one reaction. Successive acidic workup generated a variety of 1,4-diketones from substituted benzylzine chlorides or related compounds and α,β-enones. Some products were converted to cyclopentenones or five-membered heterocyclic compounds containing an N, O, or S atom.
Mercuric triflate-catalyzed synthesis of 2-methylfurans from 1-alkyn-5-ones
Imagawa, Hiroshi,Kurisaki, Takahiro,Nishizawa, Mugio
, p. 3679 - 3681 (2007/10/03)
(Chemical Equation Presented) 2-Methylfurans were prepared by an effective cyclization of 1-alkyn-5-ones in the presence of mercuric triflate as the catalyst under very mild reaction conditions with high catalytic turnover up to 100 times. Benzene, toluen
Addition of Aldehydes to Activated Double Bonds, XXXV. α-Keto Acids as an Equivalent for Aldehydes in the Thiazolium Salt-Catalyzed Addition
Stetter, Hermann,Lorenz, Guenther
, p. 1115 - 1125 (2007/10/02)
α-Keto acids can be used instead of aldehydes in the thiazolium salt-catalyzed addition to vinyl ketones.The yields of γ-diketones 1-7 resulting from the aliphatic α-keto acids are equivalent with those obtained from the aldehydes.The diketo acids 9-19 are prepared from the easily accessible 2-oxodiacids.Phenylpyruvic acids are easier to prepare than the phenylacetaldehydes and give better yields compared with the corresponding aldehydes in the addition to vinyl ketones leading to the γ-diketones 20-29.These diketones are converted to cyclopentenones.The dihydrofurylglyoxylic ester 40 leads to the diketone 43, which is converted to the diketone 44.There is no aldehyde known equivalent to that keto acid.
