32778-08-8 Usage
Uses
Used in Pharmaceutical Industry:
1-Chloro-2,2,2-trifluoroethyl chlorodifluoroMethyl ether is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
1-Chloro-2,2,2-trifluoroethyl chlorodifluoroMethyl ether is used as a reagent in various chemical reactions, such as nucleophilic substitutions and elimination reactions. Its ability to participate in these reactions allows for the formation of new chemical entities with diverse applications.
Used in Research and Development:
1-Chloro-2,2,2-trifluoroethyl chlorodifluoroMethyl ether is utilized in research laboratories for the investigation of its chemical properties and potential applications. Its unique structure and reactivity make it an interesting subject for scientific studies, which may lead to the discovery of new uses and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 32778-08-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,7 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 32778-08:
(7*3)+(6*2)+(5*7)+(4*7)+(3*8)+(2*0)+(1*8)=128
128 % 10 = 8
So 32778-08-8 is a valid CAS Registry Number.
32778-08-8Relevant academic research and scientific papers
Chiral interactions of the fluoroether anesthetics desflurane, isoflurane, enflurane, and analogues with modified cyclodextrins studied by capillary gas chromatography and nuclear magnetic resonance spectroscopy: A simple method for column-suitability screening
Ramig, Keith,Krishnaswami, Ashok,Rozov, Leonid A.
, p. 319 - 330 (2007/10/02)
Eighteen chiral analogues of the chiral fluoroether anesthetics desflurane, isoflurane, and enflurane are synthesized and studied by capillary GC on four cyclodextrin-derived stationary phases. Trends in separability and elution order of enantiomers are related to structure and absolute configuration. In particular, a very large separation factor is found for the commercial anesthetic desflurane using Lipodex E stationary phase, suggesting that a preparative enantiomer separation is possible. One of the stationary phases, Cyclodex G-TA, is found to be a chiral shift reagent for several of the fluoroethers. A rough correspondence is found relating the enantiomeric separation factor of a fluoroether and the chemical shift differences between its 1H and 19F nuclei in the NMR spectrum. Based on this data, it is proposed that a simple NMR experiment can screen chiral stationary phases prior to a desired gas chromatographic enantiomer separation of a given chiral compound. Copyright
