32787-78-3Relevant articles and documents
Re-arrangements of 4-[(4H-1,2,4-triazol-4-ylimino)methyl]phenol with different inorganic anions: Crystal structure and fluorescence properties
Zhang, Ya-Wen,Wang, Jing-Wen,Wu, Hong-Shuai,Wang, Ming-Xin,Luo, Yang-Hui,Sun, Bai-Wang
, p. 203 - 212 (2017)
Fluorescent materials have many interesting applications, but it remains difficult to control the luminescence of organic materials and in particular to retain the same luminescence in solution and in the solid state, a property of interest for various imaging applications. In this work, the influence of inorganic-anions on the crystal structure and physical–chemical properties of a series organic salts L+Cl? (1), L+ClO4? (2), L+NO3?·H2O (3), 2L+SO42?·2H2O (4) (L?=?4-[(4H-1,2,4-triazol-4-ylimino)methyl]phenol) has been investigated. Single crystal X-ray analyzes revealed that salt 1 formed a linear structure connected by H?O interactions, while salts 2–4 all formed 2D network structures through O?O interactions. The protonated L+s adopt face-to-face slipped π-stacked arrangement in salts 1 and 3, while display monomer arrangements in 2 and 4, the latter can be attribute to the entrapment of heavy anions in the crystal lattices. Optical-properties measurements of these four salts have shown L+ arrangements dependent on solid-state properties: salt 1 and 3 show broad emission bands (λ1?=?478?nm, λ2?=?487?nm) with a red shift of about 60?nm relative to its fluorescence in solvents, while 2 and 4 are similar to each other, exhibiting sharp bands (λ3?=?453?nm, λ2?=?433?nm) with the higher ?PL values (?PL1?=?0.08, ?PL1?=?0.15, ?PL1?=?0.06, ?PL1?=?0.14). These results demonstrated the significant influence of inorganic-anions on the organic salts and the optical properties of organic materials could be modulated by entrapping different anions in lattice.
Novel triazole containing zinc(II)phthalocyanine Schiff bases: Determination of photophysical and photochemical properties for photodynamic cancer therapy
Harmandar, Kevser,Saglam, Mehmet F.,Sengul, Ibrahim F.,Ekineker, Gül?in,Balcik-Ercin, Pelin,G?ksel, Meltem,Atilla, Devrim
, (2021)
A simple and efficient synthesis of novel zinc(II) phthalocyanines bearing triazole moieties was described. The synthetic approach for preparation of the phthalocyanines 1 and 13 was achieved by Schiff base condensation reaction of phthalocyanine tetracarbaldehydes 3 and 12 with 4-amino-4H-1,2,4-triazole 5 in tetrahydrofuran in reasonable yields. The photophysical and photochemical properties of the compounds 1, 3, 12 and 13 were recorded only in DMSO. The singlet oxygen generation ability of the targeted phthalocyanine Schiff bases were investigated in an attempt to understand their potential for photodynamic therapy (PDT) activity. Moreover, in vitro PDT application was performed against the MCF-7 and MDA-MB-231 invasive breast carcinoma cell lines. Preliminary assay showed that the compounds 1 and 13 possessed the phototoxicity and cytotoxicity, with a maximum of 30% MCF-7 cells dead following light irradiation. It was also revealed that the targeted phthalocyanines possess promising characteristic as photosensitizer towards tumor cells.
Antiglycation activity of triazole schiff’s bases against fructose-mediated glycation: In vitro and in silico study
Choudhary, Muhammad I.,Imad, Rehan,Khan, Khalid M.,Naqeeb, Uzma,Shaikh, Muniza,Siddiqui, Salman,Subzwari, Fakiha,Zafar, Humaira
, p. 575 - 591 (2020/06/21)
Background: Advanced glycation end products (AGEs) are known to be involved in the pathophysiology of diabetic complications, neurodegenerative diseases, and aging. Preventing the formation of AGEs can be helpful in the management of these diseases. Objec
Synthesis and biological screening of some new thiophene and pyrazole containing styrylchromones and pyrazoles
Mhaske, Sadhana D.,Takate, Sushama J.,Dhawale, Rhushikesh N.,Akolkar, Hemantkumar N.,Randhavane, Pratibha V.,Karale, Bhausaheb K.
, p. 89 - 97 (2019/01/16)
Series of brominated thiophene anchored 2-styrylchromones and styrylpyrazoles were synthesized using Baker-Venkataraman transformation. The structures of newly synthesized compounds were confirmed by spectral techniques such as infrared, 1H nuc
