32791-63-2Relevant academic research and scientific papers
Easy saponification by metal silanolates: Application in SPPS and in (S)-5-hydroxynorvaline preparation
Minta, Ewelina,Boutonnet, Cédric,Boutard, Nicolas,Martinez, Jean,Rolland, Valérie
, p. 1795 - 1797 (2007/10/03)
Alkali metal trimethylsilanolates, TMSO-, M+, has been used for efficient conversion of methyl esters into their corresponding anhydrous acid salts under mild non-aqueous conditions. This strategy has been applied to SPPS for the preparation of neurotoxin cyclic analogues and in (S)-5-hydroxynorvaline synthesis.
