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NOMIFENSINE MALEATE SALT is a synthetic compound that functions as an antidepressant and dopamine uptake inhibitor. It is structurally related to amphetamine and has been utilized in the treatment of depression due to its ability to increase the levels of dopamine in the brain. Additionally, it has been employed in research settings to study the binding of β-CFT, a cocaine analogue, using human embryonic kidney 293T cells.

32795-47-4

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32795-47-4 Usage

Uses

Used in Pharmaceutical Industry:
NOMIFENSINE MALEATE SALT is used as an antidepressant medication for the treatment of depression. It works by inhibiting the reuptake of dopamine, thereby increasing its levels in the brain and alleviating depressive symptoms.
Used in Research Applications:
NOMIFENSINE MALEATE SALT is used as a research tool for studying the β-CFT (cocaine analogue) binding in human embryonic kidney 293T cells. This application aids in understanding the mechanisms of action and potential therapeutic uses of drugs that target the dopamine transporter.

Therapeutic Function

Psychostimulant

Biochem/physiol Actions

Nomifensine maleate is a selective dopamine uptake inhibitor interacting with the dopamine transporter, at a site different from that of cocaine; antidepressant. Nomifensine serves as an antidepressant and is known to cause frequent hemolytic anemia. The aniline group in NOMIFENSINE MALEATE SALT results in blood and liver toxicities.

Safety Profile

Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by intravenous route: heart ratechanges, blood pressure elevation. Experimentalreproductive effects. An antidepressant. When heated to decomposition it em

Check Digit Verification of cas no

The CAS Registry Mumber 32795-47-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,9 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 32795-47:
(7*3)+(6*2)+(5*7)+(4*9)+(3*5)+(2*4)+(1*7)=134
134 % 10 = 4
So 32795-47-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H24N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h5,8-9,12,14H,2-4,6-7,10-11,17H2,1H3

32795-47-4 Well-known Company Product Price

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  • Sigma

  • (N1530)  Nomifensine maleate salt  

  • 32795-47-4

  • N1530-100MG

  • 2,545.92CNY

  • Detail

32795-47-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Nomifensine maleate salt

1.2 Other means of identification

Product number -
Other names Nomifensine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32795-47-4 SDS

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